Answer the following questions : a. how is p53 related to oncogenes and tumor suppressor genes? b. How is a mutated oncogene analogous to a 100-point weight on the gas pedal of a car? c. Relate this to the retroviral mechanism of transformation d. How does the car analogy apply to a mutated tumor suppressor gene?
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p53 is a tumor suppressor gene that plays a crucial role in preventing the development of cancer. It regulates the cell cycle and initiates apoptosis (programmed cell death) in cells with damaged DNA. Oncogenes, on the other hand, are genes that promote cell Show more…
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Select TWO statements that accurately describe oncogenes and/or tumor suppressor genes. Inactivation of tumor suppressor genes leads to tumor formation Proto-oncogenes play essential roles in cell signaling Activation of tumor suppressor genes leads to tumor formation Oncogenes act in a recessive fashion Two copies of oncogene are needed for tumor formation Tumor suppressor genes act in dominant fashion
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Which of the following accurately compares tumor suppressor genes and proto-oncogenes? Choose the answer. A person who has both tumor suppressor and proto-oncogenes will not always develop cancer. When a proto-oncogene mutates, it becomes an oncogene, not a tumor suppressor gene. Both tumor suppressor genes and proto-oncogenes prevent the spread of cancer by targeting and destroying existing cancer cells. Proto-oncogenes code for growth factors, while tumor suppressor genes inhibit the cell division of damaged cells.
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Which of the following is a tumor suppressor gene (or the product of a tumor suppressor gene)? Select all answers that apply: A. Raf B. Her2 receptor C. PTEN D. INK4a E. p53
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