Question

Approximately 50 million SNPs have thus far been recorded after the characterization of thousands of human genomes. a. About how many base pairs in the human genome are identical in these thousands of people? b. Do you think that many other SNPs exist among the human population? If so, why haven't they been found? c. Almost all of the SNP polymorphisms found to date are biallelic; that is, among all the genomes in the population studied to date, only two possible alleles can be found (for example, $A$ and $C$ ). Provide a rough estimate for the number of triallelic SNP loci that could be found in the same group of humans (that is, the number of loci with three different alleles - for example, $A, C,$ and $T$ ). At about how many loci would all four possible nucleotides be found among the human genomes studied to date?

          Approximately 50 million SNPs have thus far been recorded after the characterization of thousands of
human genomes.
a. About how many base pairs in the human genome are identical in these thousands of people?
b. Do you think that many other SNPs exist among the human population? If so, why haven't they been found?
c. Almost all of the SNP polymorphisms found to date are biallelic; that is, among all the genomes in the population studied to date, only two possible alleles can be found (for example, $A$ and $C$ ). Provide a rough estimate for the number of triallelic SNP loci that could be found in the same group of humans (that is, the number of loci with three different alleles - for example, $A, C,$ and $T$ ). At about how many loci would all four possible nucleotides be found among the human genomes studied to date?

Added by Allison G.

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