b. Calculate the probability of a resident of Bogotá having the partial genetic fingerprints of two of the twins (Carlos and Jorge). (10 points) 1) Probability of having Carlos's genotype for the individual loci: (3 points) D8S1179: 0.6 D18S51: 0.4 ????: 0.9 2) Probability of having Jorge's genotype for the individual loci: (3 points) D8S1179: 0.7 D18S51: 0.9 ????: 0.8 3) Calculate the probability of having Carlos's partial profile. (2 points) 4) Calculate the probability of having Jorge's partial profile. (2 points)
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- D8S1179: 0.6 - D18S51: 0.4 - TPOX: 0.9 Show more…
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A suspect in a crime has the following genotype at three separate and unlinked biallelic loci, A, B and C: A1/A2; B2/B2; C2/C2. Blood found at the scene of the crime is seen to match this genotype. The allele frequencies of alleles A1, B1, C2 in the population are 0.9, 0.8, and 0.7 respectively. What is the chance that this match with the suspect occurs simply by chance alone? (Assume Hardy-Weinberg proportions for each locus)
Adi S.
hhmi BioInteractive CASE STUDY: Switched at Birth? Calculate the probability of having a given genetic fingerprint, the probabilities of having each STR genotype are multiplied. c. Calculate the probability of having Carlos's partial profile. Show your work. = (8.41 x 10^-4) (1.11 x 10^-2) (1.296 x 10^-3) = 1.21 x 10^-8 d. Calculate the probability of having Jorge's partial profile. Show your work. = (2.05 x 10^-2) (2.59 x 10^-2) (6.4 x 10^-5) = 3.3 x 10^-8 3. Were the sets of twins switched at birth? Explain your answer using evidence from their partial genetic fingerprints and calculations. Yes, since their DNA profile almost match exactly to one another and that can only happen with identical twins 4. Explain why DNA fingerprints are a more reliable method of determining family relationships than blood typing. Hint: How many different blood types are there? How many different possible DNA fingerprints? There are only 4 different blood types but 13 different STR loci to test for, and there are extremly low chances to have all 13 loci matching to someone else, it more reliable. 5. Can you think of a way that this discovery of identical twins switched at birth would provide scientists with an opportunity to see how certain traits are affected by the environment?
Assume that there is complete dominance and complete penetrance at each locus and that epistasis does not occur. (These are the same conditions we used in class). Write your answers in numeric form (not in words). Referring to the cross DdFFGghhRrTT x DDffGgHhRRTt: How many different gametes does the DdFFGghhRrTT parent produce? How many different genotypes are found among the progeny of this cross? How many different phenotypes are found among the progeny of this cross? What is the probability that the first offspring from this cross will show the dominant phenotype for all loci? (Type in as a decimal and round to 6 digits.) What is the probability that the first offspring from this cross will be heterozygous for all loci? (Type in as a decimal and round to 6 decimal digits.) What is the probability that the first offspring from this cross will be a son with genotype DDFfGghhRrTt? (Type in as a decimal and round to 6 decimal digits).
Bryan V.
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