B. GABA-Gated Ionotropic Receptors: What are these? How do they work? How are they enhanced by Benzodiazepines & Barbiturates? 2. Metabotropic Receptors: G-protein Coupled Recptors a. Explain the structure of G-protein-coupled receptors b. What are the GENERAL steps involved in transmission at these receptors? c. Describe the G-protein-coupled effector systems/pathways (discussed in class): d. Explain why ACh slows heart rate. e. Discuss phosphorylation and dephosphorylation of ion channels. In addition, discuss the function of signal cascades and the role of protein phosphatases.
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GABA-gated ionotropic receptors are a type of ligand-gated ion channel that primarily allows the passage of chloride ions (Cl-) across the cell membrane. They are activated by the neurotransmitter gamma-aminobutyric acid (GABA), which is the primary inhibitory Show more…
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