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Background The PV19 Alu transposon is a mobile pseudogene present in some of the human population on Chromosome 16, at a location referred to as PV19. Presence of this 300 base-pair long bit of DNA is denoted with a (+) and the absence of this 300 bp fragment in the locus in denoted with a (-). *How many copies of of the Chromosome 16 PV19 locus are there in the population sample below? (1pt) *What are the frequencies of the (+) and (-) alleles of the PV19 locus in this sample population? (4pts) +/+ = 3 individuals +/- = 11 individuals -/- = 6 individuals 

          Background The PV19 Alu transposon is a mobile pseudogene present in some of the human population on Chromosome 16, at a
location referred to as PV19. Presence of this 300 base-pair long bit of DNA is denoted with a (+) and the absence of this 300 bp
fragment in the locus in denoted with a (-).
*How many copies of of the Chromosome 16 PV19 locus are there in the population sample below? (1pt)
*What are the frequencies of the (+) and (-) alleles of the PV19 locus in this sample population? (4pts)
+/+ = 3 individuals
+/- = 11 individuals
-/- = 6 individuals
Show more…
Background The PV19 Alu transposon is a mobile pseudogene present in some of the human population on Chromosome 16, at a location referred to as PV19. Presence of this 300 base-pair long bit of DNA is denoted with a (+) and the absence of this 300 bp fragment in the locus in denoted with a (-). *How many copies of of the Chromosome 16 PV19 locus are there in the population sample below? (1pt) *What are the frequencies of the (+) and (-) alleles of the PV19 locus in this sample population? (4pts) +/+ = 3 individuals +/- = 11 individuals -/- = 6 individuals

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Biology for AP Courses
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Julianne Zedalis, John Eggebrecht
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Background The PV19 Alu transposon is a mobile pseudogene present in some of the human population on Chromosome 16, at a location referred to as PV19. Presence of this 300 base-pair long bit of DNA is denoted with a (+) and the absence of this 300bp fragment in the locus in denoted with a (-). How many copies of of the Chromosome 16 PV19 locus are there in the population sample below? (1pt) *What are the frequencies of the (+) and (-) alleles of the PV19 locus in this sample population? (4pts) (+)/(+)=3 individuals (+)/(-)=11 individuals (-)/()=6 individuals Background The PV19 Alu transposon is a mobile pseudogene present in some of the human population on Chromosome 16,at a location referred to as PV19.Presence of this 300 base-pair long bit of DNA is denoted with a +) and the absence of this 300 bp fragment in the locus in denoted with a (-). *How many copies of of the Chromosome 16 PV19 locus are there in the population sample below?(1pt) *What are the frequencies of the (+) and (-) alleles of the PV19 locus in this sample population? (4pts) +/+=3individuals +/-=11individuals -/--=6individuals
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Transcript

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00:01 So a allele element or class of short interspersed element in human genome.
00:06 So you know that it's approximately 300 base pairs in length.
00:10 You're studying an allele of well -characterized gene that results from allele insertion.
00:15 There are two different bands.
00:17 You know that when you have an allele insertion, into the interim you'll actually see a 454 base pair band.
00:31 And without insertion, you will actually have a 142 base pair band.
00:41 Now you have 18 lanes.
00:44 The first one is the marker and number four doesn't show up.
00:49 So this means that you have altogether 17 samples.
00:57 Now out of these samples, the question asks you to calculate the allele frequency of allele containing allele in this population.
01:13 Let's say you have 17 samples.
01:18 And if we look at the one with insertion, you'll see a band at 454 base pairs...
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