Based on the chymotrypsin mechanism discussed in class, which of the following is true for the first step of the mechanism? a) The carbon of the carbonyl group of the substrate changes its hybridization from sp2 to sp3 after nucleophilic attack. b) The exit of one of the products of the active site of the enzyme occurs. c) The formation of the intermediate "acyl-enzyme" occurs. d) A water molecule is deprotonated by His 57. e) Substrate peptide bond breaking occurs.
Added by Jennifer S.
Step 1
Step 1: The chymotrypsin enzyme binds to the substrate in its active site. Show more…
Show all steps
Your feedback will help us improve your experience
Suman K and 101 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Which of the following statements about peptide bonds are true? A. Peptide bonds are amide linkages. B. Peptides are polymers of amino acids. C. Peptide bond formation is a condensation reaction. D. A tripeptide contains three amino acid residues. E. Peptide bonds form from nucleophilic attack by an α-carbon atom on an electron pair of an α-amino nitrogen atom of another amino acid.
Adi S.
Which of the following statements about reaction mechanisms are true? Select all that apply. A. The polymerization of amino acids to form polypeptides is an example of an addition reaction. B. Hydration is an example of an addition reaction C. A carbon atom carrying a positive charge is called a carbocation D. Esterification is an example of a condensation reaction. E. Addition only occurs across the C=C double bond.
Rabia B.
Choose the incorrect statement: a. Peptide bonds are formed through hydrolysis. b. Vitamins sometimes help an enzyme convert substrate to product. c. The primary structure of a protein is the precise sequence of amino acids. d. Quaternary structure results from attractive forces between the subunits of a protein.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD