Before an organ transplant, tests are conducted to ensure...

Before an organ transplant, tests are conducted to ensure that a recipient and donor are compatible. If a recipient and donor are compatible, there is a possibility that an organ can be transferred from the donor to the recipient, and that the recipient's immune system will recognize the new organ as "self". However, if the recipient and donor are not compatible, the recipient's immune system will recognize the organ as foreign and reject the organ transplant. What proteins are tested to determine compatibility between an organ donor and an organ recipient? cadherins on the surface of cells comprising the organ tissue human leukocyte antigens (HLAs) on the surface of most nucleated cells DNA polymerase within the cells comprising the organ tissue constant region of antibodies produced by B cells cluster of differentiation 8 (CD8) on the surface of T cells

Transcript

00:01 Hello friends this question is about organ transplantation when any person to transplant means what happens person with liver or kidney it is infected or not working properly at that time these organs must be transplanted from healthy person so if organ transplantation we want some conditions are there because we cannot pick up any organ from any random person and it is adjusted in the body of another person randomly we cannot do this process because number of factors they are responsible because main problem is the organ rejection organ rejection because our body have one facility that our body recognize actually our body recognize self and non -self cells.

01:09 Self and non -self or foreign selves.

01:16 And non -self, these are considered as an antigens.

01:22 And when they are considered as an antigens, our body treat them like a they are pathogen ones.

01:29 And as they are considered as a pathogen, bodies start to produce.

01:33 Our bodies start to produce antibodies against these.

01:37 These antigens.

01:38 Body produce antibodies against these antigens and these antibodies are responsible for organ rejection and automatically that organs fail to work in our body, fail to adjust in our body and this is a main problem.

01:57 So what they are asking before transferring any or before transplantation of any organ in body, there are some factors and these competitively must be there between donor and organ recipients.

02:12 So which tastes are there or involved, they have to perform by doctors.

02:19 That first is a catherines, surface cells, these are present on surface of cells.

02:24 These are, this taste is not required actually because these are, these catherins, these are responsible for cell adhesion.

02:33 Means our body is made up of cells and these cells must be adhered to each other that's why this cell will form tissue and tissue will form then organs so these surface these are catheterine these are present on surface of cell so test is not important for this purpose so this is wrong one when we talk about three tests means when organ donation taking place at that time there are three important tests that must be performed and these first test is a blood test second one is a cross match of tissues cross match of tissues and last is a hla test this is a third test and this is only given in option human leukocyte antigen hla test must be done because these leukocytes form antigens antibodies against antigens so human leukocyte antigens each leukocyte in every body this is a specific one blood group as they are also specific ones so these tests are important to perform before transferring or transplantation of any organs.

04:12 So this is right one...

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