Below is a partlal pedigree of hemophilia in the British Royal Family descended from Queen Victoria, who is belicved to be the original "carrier" in this pedigree. Analyze the pedigree and indicate which females are also certain to be carriers. What is the probability that Princess Irene is a carrier?
Added by Julie J.
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Queen Victoria is a carrier, so she has one normal allele (N) and one hemophilia allele (h). Show more…
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Below is a partial pedigree of hemophilia in the British Royal Family descended from Queen Victoria, who is believed to be the original "carrier" in this pedigree. Analyze the pedigree and indicate which females are also certain to be carriers. What is the probability that Princess Irene is a carrier?
There is a $50-50$ chance that the queen carries the gene of hemophilia. If she is a carrier, then each prince has a $50-50$ chance of having hemophilia independently. If the queen is not a carrier, the prince will not have the disease. Suppose the queen has had three princes without the disease, what is the probability the queen is a carrier?
Probability
Bayes' Rule
There is a $50-50$ chance that the queen carries the gene of hemophilia. If she is a carrier, then each prince has a $50-50$ chance of having hemophilia independently. If the queen is not a carrier, the prince will not have the disease. Suppose the queen has had three princes without the disease. What is the probability the queen is a carrier?
Lucas F.
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