11. Below is a pedigree chart of an autosomal recessive...

11. Below is a pedigree chart of an autosomal recessive disorder. Answer the following questions using the correct genetic terminology (do not just write letters like "Ee"). A. What is the genotype of individual 1 in generation II? B: What is the genotype of individual 2 in generation I? C: Is it true that individuals 6, 7, 8, 9, and 10 in generation III all have the same genotype? Why or why not?

Transcript

00:01 Okay, going to answer this question, let's talk about pedigris, okay? it says below is a pedigris chart of an autosomal recessive disorder.

00:08 I think it is, they are telling us to use these allele, the dominant allele and the recessive allele.

00:14 So a series of autosomal recessive disorder and this is going to be a normal allele and this is going to be the mutant allele or the allele for the disease.

00:24 So when you have this genotype, you're going to be a normal person.

00:30 When you have this genotype, you're going to be also a normal person, but you're going to be a carrier because you have this mutant alleles.

00:39 Okay, but as you have the dominant allele in the genotype, it is going to dominate over this allele and you're not going to express a disease.

00:45 And when you have the homozyrocessive, you're going to have the disease.

00:52 It says, answer the following questions using the genetic technology.

00:55 Don't just write later like this.

00:58 So it says, what is the genotype of individual one in generation two? they are asking you about this one here.

01:05 Remember that if this is, for example, let's suppose that this is a genotype for 2 -1, it means for this person here.

01:14 Okay, and this is the mother and this is the father.

01:18 It's the mother and this is the father.

01:20 Remember that this person is going to inherit one allele from the mother and one all the father.

01:25 Okay, so for example, this model is going to have a genotype and she's going to transmit one of these alleles from her genotype to this child.

01:34 Okay, and the same from the father.

01:36 So this person has two recessive alleles.

01:40 Then it means that she, because she's a woman, okay, that she received one recessive all from the mother and one recessive all right.

01:47 So both of them, both parents should have at least one recessive allele.

01:52 So they can be like this homozygly or they can be heterocyboes.

01:58 But according to this, you can see that both don't have a disease.

02:02 This genotype calls for the disease phenotype.

02:06 But this genotype calls for a normal person...

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