(c) (i) (ii) (iii) Penicillin G and ampicillin (structures shown below) are medications used to manage and treat a wide range of infections. One of the two drugs shown can be given orally, while the other can be administered intravenously. Penicillin G S X COOH NH₂ HH Ampicillin -S COOH Briefly describe how these penicillin antibiotics are able to act as bactericidal agents. Identify any TWO binding group in penicillin G or in ampicillin molecule and sketch the interactions that they can form. Which of the two agents can be administered orally? Explain how the difference in their structures leads to this difference in route of administration. [22 marks]
(c) while the other can be administered intravenously
NH2
COOH Ampicillin
HOOH Penicillin G
(i)
Briefly describe how these penicillin antibiotics are able to act as bactericidal agents. (ii) Identify any TWO binding group in penicillin G or in ampicillin molecule and sketch the interactions that they can form (ii) Which of the two agents can be administered orally? Explain how the difference in their structures leads to this difference in route of administration. [22 marks]