00:01
In order to answer this question, let's talk about receptors and transduction pathways.
00:04
It says caffeine blocks the activity of cyclic amp phosphorystaries in the epinephrine pathway.
00:11
Therefore, caffeine ingestion would interact with this pathway by.
00:16
Remember that if this is your cell, here you're going to have a receptor that is called g -protein -couple receptor, because in the intracellular it is attached to that, to a g -protein that has an alpha subunit, a beta -subunit, and a gamma subunit.
00:35
Normally when epinephrine, this is the receptor of a pinnephenephrine, okay? when epinephrine is not bound to this receptor, this alpha subjunit is going to be bound to gdp.
00:44
It means it is inactive, okay? but once epinephrine comes and binds here, then this gdp is going to be removed and it is going to bind to gtp.
00:57
And once it binds to gtp, this alpha subunit is going to detach from bida and gamma subunits, and it is going to go and activate an enzyme called adenylylylylyl cyclase.
01:07
The adenylylylyl cyclase is going to break atp down to cyclic amp.
01:13
So the levels of cyclic amp are going to guys.
01:15
This epinephrine is the first messenger, and this increased levels of cyclic amp are a second messenger...