Caffeine inhibits 3', 5'-cAMP phosphodiesterase, which converts cAMP to AMP. Which of the following effects would be observed if cells were treated with caffeine? A. Decreased activity of protein kinase A B. Decreased activity of phosphorylase kinase C. Decreased activity of glycogen synthetase D. All of the above
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This leads to an increase in cAMP levels in the cell. Increased cAMP levels activate protein kinase A (PKA). So, we would observe an increase in the activity of protein kinase A, not a decrease. Show more…
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