Cancer often involves excessive and uncontrolled mitosis, resulting in a tumour. Some of the chemotherapeutic agents used in cancer therapy inhibit DNA replication. a) Propose and explain two possible ways that chemotherapy drugs can inhibit replication. b) While this is sometimes successful in stopping tumour growth, there are side effects. What do you think these side effects might be? a. The two possible ways that chemotherapy drugs can inhibit replication is by upregulation the tumor suppressor genes that are involved in the replication for example P53 or p21 and also by down regulation proto-oncogenes. b.The sides effects of
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These genes are involved in regulating cell division and can help stop the uncontrolled growth of cancer cells. Show more…
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Many human cancers result when a normal gene mutates and leads to uncontrolled growth (a tumor). Genes that cause cancer when they mutate are called oncogenes. Chemotherapy is effective against many tumors because it targets rapidly dividing cells and kills them. Unfortunately, chemotherapy has many side effects, such as hair loss or nausea, because it also kills many of our normal cells that are rapidly dividing, such as those in the hair follicles or stomach lining.Many scientists and large pharmaceutical companies are excited about the prospects of exploiting the RNAi pathway to selectively inhibit oncogenes in lifethreatening tumors. Explain in very general terms how gene-silencing therapy might work to treat cancer and why this type of therapy would have fewer side effects than chemotherapy.
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some nonsurgical cancer treatment involve the interference of DNA replication. Cancer treatment is known as pyrimidine analogs, which are altered pyrimidine rings. they have the same ring structure, but differ with at a specific element. the difference in molecule stops the addition of nucleotides during DNA replication. 1. Why must this be a good cancer treatment for patients based on your knowledge of the cell cycle and DNA replication 2. Explain with details how can this medication influence this process.
Adi S.
Cancer cells are said to be metastatic when they a. begin to divide uncontrollably. b. invade healthy tissue. c. migrate to other parts of the body. d. cause mutations in other healthy cells. e. do all of the above.
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