Question

Clinical Case: A Tired Freshman A Tired Freshman: An 18-year-old college freshman reports to the campus health clinic. He states that he has felt very fatigued and generally ill for about a week and developed a sore throat, fever, and headache the day before. He has been sleeping more than usual and has virtually no appetite. He says his girlfriend, who attends college in a different state and whom he saw last month, has also been feeling very fatigued for the last two weeks or so, but she displays none of the student's other symptoms. Part A Which disease and causative agent pair would be responsible for these symptoms? 1. Lyme disease caused by Borrelia burgdorferi 2. Malaria caused by Plasmodium falciparum 3. Infectious mononucleosis caused by the Epstein-Barr virus (EBV) 4. Ehrlichiosis caused by Ehrlichia chaffeensis Part B How is this disease transmitted? 1. The exchange of saliva while sharing a straw, a drinking glass, or while coughing or sneezing 2. The infection is spread by a fecal-oral route like polio 3. The exchange of bodily fluids or blood products during sexual contact, as with HIV 4. Physical contact during your daily routine like the herpesvirus Part C: The suppression of apoptosis on account of infection with EBV may lead to the development of which disease in patients with suppressed immune systems? 1. Burkitt's lymphoma 2. Lymph node swelling (lymphadenopathy) or "buboes" 3. Severe arthritis 4. Chagas' disease Part D: What is the best treatment regime for people suffering from infectious mononucleosis? 1. Treatments should include chloroquine and bed rest. 2. Alleviate the symptoms and allow the patient's immune system to clear the virus-infected cells. 3. Isolation, bed rest, and treatment with rifampin will slow the progression of the disease. 4. An antibiotic such as penicillin or amoxicillin will stop the spread of the infection. Part E: The girlfriend is not showing the same symptoms as her boyfriend but a reduced set of symptoms; which of the following would not be a good explanation for this? The girlfriend is not showing the same symptoms as her boyfriend but a reduced set of symptoms; which of the following would not be a good explanation for this? 1. She is lacking an immune system. 2. She was exposed at an early age and now has immunity to the virus. 3. She is exhibiting chronic fatigue syndrome on account of infectious mononucleosis infection. 4. She will develop the symptoms in a few days since she is still in the incubation period for the viral infection.

Clinical Case: A Tired Freshman
A Tired Freshman: An 18-year-old college freshman reports to the campus health clinic. He states that he has felt very fatigued and generally ill for about a week and developed a sore throat, fever, and headache the day before. He has been sleeping more than usual and has virtually no appetite. He says his girlfriend, who attends college in a different state and whom he saw last month, has also been feeling very fatigued for the last two weeks or so, but she displays none of the student's other symptoms.

Part A
Which disease and causative agent pair would be responsible for these symptoms?
1. Lyme disease caused by Borrelia burgdorferi
2. Malaria caused by Plasmodium falciparum
3. Infectious mononucleosis caused by the Epstein-Barr virus (EBV)
4. Ehrlichiosis caused by Ehrlichia chaffeensis

Part B
How is this disease transmitted?
1. The exchange of saliva while sharing a straw, a drinking glass, or while coughing or sneezing
2. The infection is spread by a fecal-oral route like polio
3. The exchange of bodily fluids or blood products during sexual contact, as with HIV
4. Physical contact during your daily routine like the herpesvirus

Part C: The suppression of apoptosis on account of infection with EBV may lead to the development of which disease in patients with suppressed immune systems?
1. Burkitt's lymphoma
2. Lymph node swelling (lymphadenopathy) or "buboes"
3. Severe arthritis
4. Chagas' disease

Part D: What is the best treatment regime for people suffering from infectious mononucleosis?
1. Treatments should include chloroquine and bed rest.
2. Alleviate the symptoms and allow the patient's immune system to clear the virus-infected cells.
3. Isolation, bed rest, and treatment with rifampin will slow the progression of the disease.
4. An antibiotic such as penicillin or amoxicillin will stop the spread of the infection.

Part E: The girlfriend is not showing the same symptoms as her boyfriend but a reduced set of symptoms; which of the following would not be a good explanation for this?
The girlfriend is not showing the same symptoms as her boyfriend but a reduced set of symptoms; which of the following would not be a good explanation for this?
1. She is lacking an immune system.
2. She was exposed at an early age and now has immunity to the virus.
3. She is exhibiting chronic fatigue syndrome on account of infectious mononucleosis infection.
4. She will develop the symptoms in a few days since she is still in the incubation period for the viral infection.

Added by Raquel S.

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