Congenital ectodermal dysplasia - defect in desmosomes causing skin that easily separates from deeper layers
Added by Matthew W.
Step 1
Step 1: Understand the condition - Congenital ectodermal dysplasia is a genetic disorder that affects the development of ectodermal structures, including skin, hair, nails, and teeth. Show more…
Show all steps
Your feedback will help us improve your experience
Danielle Ashley and 57 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Diseases in humans that have a clinical presentation of severe and extensive blistering of the skin can result from defects in many (or any) components of desmosomes and hemidesmosomes or even proteins that function as cytoskeletal cross-linkers. Which of the following is unlikely to be defective in blistering diseases? A. keratin (a cytosolic IF protein) B. plectin (a linker of intermediate filaments [IFs] to other IFs) C. desmoglein (a cadherin, a cell adhesion molecule) D. lamin (a nuclear IF protein)
Danielle A.
The condition epidermolysis bullosa is characterized by repeated blister formation resulting from only minor trauma. Several forms of the disease are caused by mutations in genes coding for keratin proteins. Why would defective keratin lead to an inability to resist mechanical stresses?
Tracy L.
Defect in one of the keratin genes would most likely cause what symptom? Premature aging Hearing loss Infertility Skin blisters Cancer
Marlyn J.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD