Question

Consider the CODING sequence below: What would be the corresponding mRNA sequence? Using the genetic code table, determine the corresponding Amino Acid sequence. IF the red C was DELETED, what kind of mutation would that cause (missense/nonsense/frameshift)? What would be the resulting effect on the translated peptide? The Genetic Code Second base in codon U C A G U UUU Phe F UUC Phe F UUA Leu L UUG Leu L UCU Ser S UCC Ser S UCA Ser S UCG Ser S UAU Tyr Y UAC Tyr Y UAA Stop UAG Stop UGU Cys C UGC Cys C UGA Stop UGG Trp W U C A G C CUU Leu L CUC Leu L CUA Leu L CUG Leu L CCU Pro P CCC Pro P CCA Pro P CCG Pro P CAU His H CAC His H CAA Gln Q CAG Gln Q CGU Arg R CGC Arg R CGA Arg R CGG Arg R U C A G A AUU Ile I AUC Ile I AUA Ile I AUG Met M ACU Thr T ACC Thr T ACA Thr T ACG Thr T AAU Asn N AAC Asn N AAA Lys K AAG Lys K AGU Ser S AGC Ser S AGA Arg R AGG Arg R U C A G G GUU Val V GUC Val V GUA Val V GUG Val V GCU Ala A GCC Ala A GCA Ala A GCG Ala A GAU Asp D GAC Asp D GAA Glu E GAG Glu E GGU Gly G GGC Gly G GGA Gly G GGG Gly G U C A G Coding Sequence: ATG TTC CAC ACG CTG ATA CCA GCT

          Consider the CODING sequence below: What would be the corresponding mRNA sequence? Using the genetic code table, determine the corresponding Amino Acid sequence. IF the red C was DELETED, what kind of mutation would that cause (missense/nonsense/frameshift)? What would be the resulting effect on the translated peptide?

The Genetic Code
Second base in codon
U C A G
U
UUU Phe F
UUC Phe F
UUA Leu L
UUG Leu L
UCU Ser S
UCC Ser S
UCA Ser S
UCG Ser S
UAU Tyr Y
UAC Tyr Y
UAA Stop
UAG Stop
UGU Cys C
UGC Cys C
UGA Stop
UGG Trp W
U
C
A
G
C
CUU Leu L
CUC Leu L
CUA Leu L
CUG Leu L
CCU Pro P
CCC Pro P
CCA Pro P
CCG Pro P
CAU His H
CAC His H
CAA Gln Q
CAG Gln Q
CGU Arg R
CGC Arg R
CGA Arg R
CGG Arg R
U
C
A
G
A
AUU Ile I
AUC Ile I
AUA Ile I
AUG Met M
ACU Thr T
ACC Thr T
ACA Thr T
ACG Thr T
AAU Asn N
AAC Asn N
AAA Lys K
AAG Lys K
AGU Ser S
AGC Ser S
AGA Arg R
AGG Arg R
U
C
A
G
G
GUU Val V
GUC Val V
GUA Val V
GUG Val V
GCU Ala A
GCC Ala A
GCA Ala A
GCG Ala A
GAU Asp D
GAC Asp D
GAA Glu E
GAG Glu E
GGU Gly G
GGC Gly G
GGA Gly G
GGG Gly G
U
C
A
G
Coding Sequence:
ATG TTC CAC ACG CTG ATA CCA GCT

Consider the CODING sequence below: What would be the corresponding mRNA sequence? Using the genetic code table, determine the corresponding Amino Acid sequence. IF the red C was DELETED, what kind of mutation would that cause (missense/nonsense/frameshift)? What would be the resulting effect on the translated peptide?

The Genetic Code
Second base in codon
U C A G
U
UUU Phe F
UUC Phe F
UUA Leu L
UUG Leu L
UCU Ser S
UCC Ser S
UCA Ser S
UCG Ser S
UAU Tyr Y
UAC Tyr Y
UAA Stop
UAG Stop
UGU Cys C
UGC Cys C
UGA Stop
UGG Trp W
U
C
A
G
C
CUU Leu L
CUC Leu L
CUA Leu L
CUG Leu L
CCU Pro P
CCC Pro P
CCA Pro P
CCG Pro P
CAU His H
CAC His H
CAA Gln Q
CAG Gln Q
CGU Arg R
CGC Arg R
CGA Arg R
CGG Arg R
U
C
A
G
A
AUU Ile I
AUC Ile I
AUA Ile I
AUG Met M
ACU Thr T
ACC Thr T
ACA Thr T
ACG Thr T
AAU Asn N
AAC Asn N
AAA Lys K
AAG Lys K
AGU Ser S
AGC Ser S
AGA Arg R
AGG Arg R
U
C
A
G
G
GUU Val V
GUC Val V
GUA Val V
GUG Val V
GCU Ala A
GCC Ala A
GCA Ala A
GCG Ala A
GAU Asp D
GAC Asp D
GAA Glu E
GAG Glu E
GGU Gly G
GGC Gly G
GGA Gly G
GGG Gly G
U
C
A
G
Coding Sequence:
ATG TTC CAC ACG CTG ATA CCA GCT

Added by Peter B.

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