Question

A. Consider the following DNA sequence (coding strand) located near the middle of the coding region of a gene in Neurospora. The numbers atop the nucleotides represent the position # of a nucleotide. DNA 50 55 60 65 5’- CCT G A G T C C G A G G G T G A A C G A G -3’ Which of the following DNA mutations is almost certain to result in a longer than normal mRNA? You may choose more than one answer. In any event, explain your choice(s). (3 points) • G ? A mutation at nucleotide #50 • A ? G mutation at nucleotide #54 • G ? T mutation at nucleotide #60 • None of them B. In an experiment in Neurospora, you have successfully isolated a conditional mutation that shows the following phenotypes: • At 30°C, it can synthesize DNA • At 42°C, no DNA is synthesized, and the cells die. What type of mutation is this most likely? Explain. (3 points)

          A. Consider the following DNA sequence (coding strand) located near the middle of the coding
region of a gene in Neurospora. The numbers atop the nucleotides represent the position # of
a nucleotide.

DNA

50 55 60 65
5’- CCT G A G T C C G A G G G T G A A C G A G -3’

Which of the following DNA mutations is almost certain to result in a longer than normal mRNA?
You may choose more than one answer. In any event, explain your choice(s).
(3 points)

• G ? A mutation at nucleotide #50
• A ? G mutation at nucleotide #54
• G ? T mutation at nucleotide #60
• None of them

B. In an experiment in Neurospora, you have successfully isolated a conditional mutation that
shows the following phenotypes:

• At 30°C, it can synthesize DNA
• At 42°C, no DNA is synthesized, and the cells die.

What type of mutation is this most likely? Explain. (3 points)

A. Consider the following DNA sequence (coding strand) located near the middle of the coding
region of a gene in Neurospora. The numbers atop the nucleotides represent the position # of
a nucleotide.

DNA

50 55 60 65
5’- CCT G A G T C C G A G G G T G A A C G A G -3’

Which of the following DNA mutations is almost certain to result in a longer than normal mRNA?
You may choose more than one answer. In any event, explain your choice(s).
(3 points)

• G ? A mutation at nucleotide #50
• A ? G mutation at nucleotide #54
• G ? T mutation at nucleotide #60
• None of them

B. In an experiment in Neurospora, you have successfully isolated a conditional mutation that
shows the following phenotypes:

• At 30°C, it can synthesize DNA
• At 42°C, no DNA is synthesized, and the cells die.

What type of mutation is this most likely? Explain. (3 points)

Added by Lourdes N.

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