Contrast the cause of the skin condition vitiligo with the cause of cutaneous albinism:
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The exact cause of vitiligo is not well understood, but it is believed to be an autoimmune disorder in which the immune system mistakenly attacks and destroys melanocytes. Cutaneous albinism, on the other hand, is a genetic disorder caused by a mutation in one of Show more…
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Albinism is a recessive trait in humans (see the introduction to Chapter 1). A geneticist studies a series of families in which both parents have normal pigmentation and at least one child has albinism. The geneticist reasons that both parents in these families must be heterozygotes and that albinism should appear in 14 of their children. To his surprise, the geneticist finds that the frequency of albinism among the children of these families is significantly greater than $14 .$ Can you think of an explanation for the higher-than-expected frequency of albinism among these families?
Bryan V.
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