Question

Cytosolic Ca2+ concentrations typically rise about 50-fold when Ca2+ channels open in the plasma membrane. Assume that 1000 Ca2+ channels open in a cell with a volume of 1000 mm3 and an internal Ca2+ concentration of 100 nM. Each Ca2+ channel passes 106 Ca2+ ions per second. For how long would the channels need to stay open in order to raise the cytosolic Ca2+ concentration 50-fold to 5 mM?

Name: cytosolic ca2 concentrations typically rise about 50 fold when ca2 channels open in the plasma membrane assume that 1000 ca2 channels open in a cell with a volume of 1000 mm3 and an internal 84893
Uploaded: 2023-03-25T07:22:54-08:00
Duration: 3 min 29 s
Channel: Sri K
Description: cytosolic ca2 concentrations typically rise about 50 fold when ca2 channels open in the plasma membrane assume that 1000 ca2 channels open in a cell with a volume of 1000 mm3 and an internal 84893

          Cytosolic Ca2+ concentrations typically rise about
50-fold when Ca2+ channels open in the plasma membrane.
Assume that 1000 Ca2+ channels open in a cell with a
volume of 1000 mm3 and an internal Ca2+
concentration of 100 nM. Each Ca2+ channel passes
106 Ca2+ ions per second. For how long would
the channels need to stay open in order to raise the cytosolic
Ca2+ concentration 50-fold to 5 mM?

Added by Laura G.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

Instant Answer

Solved by Expert Sri K

03/25/2023

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First, we need to find the initial number of Ca2+ ions in the cell. Show more…

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Cytosolic Ca2+ concentrations typically rise about 50-fold when Ca2+ channels open in the plasma membrane. Assume that 1000 Ca2+ channels open in a cell with a volume of 1000 mm3 and an internal Ca2+ concentration of 100 nM. Each Ca2+ channel passes 106 Ca2+ ions per second. For how long would the channels need to stay open in order to raise the cytosolic Ca2+ concentration 50-fold to 5 mM?