Question

Darleen seeks genetic counseling. Her brother died at age eight from an autosomal recessive condition. Both of their parents are deceased. The woman undergoes DNA testing (carrier screening) which collectively detects approximately 90% of carriers for this condition. Testing reveals that she is negative for all mutations screened for. What is the residual probability that she is a heterozygous carrier?

Name: darleen seeks genetic counseling her brother died at age eight from an autosomal recessive condition both of their parents are deceased the woman undergoes dna testing carrier screening whic 67808
Uploaded: 2022-05-03T18:44:01-08:00
Duration: 2 min 44 s
Channel: Anand Jangid
Description: darleen seeks genetic counseling her brother died at age eight from an autosomal recessive condition both of their parents are deceased the woman undergoes dna testing carrier screening whic 67808

          Darleen seeks genetic counseling. Her brother died at age eight from an autosomal recessive condition. Both of their parents are deceased. The woman undergoes DNA testing (carrier screening) which collectively detects approximately 90% of carriers for this condition. Testing reveals that she is negative for all mutations screened for. What is the residual probability that she is a heterozygous carrier?

Added by Tina W.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

Instant Answer

Solved by Expert Anand Jangid

05/03/2022

Step 1

Since the condition is autosomal recessive, both parents must be carriers (heterozygous) for their child to be affected. This means that Darleen's parents were likely both carriers of the condition. Show more…

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Darleen seeks genetic counseling. Her brother died at age eight from an autosomal recessive condition. Both of their parents are deceased. The woman undergoes DNA testing (carrier screening) which collectively detects approximately 90% of carriers for this condition. Testing reveals that she is negative for all mutations screened for. What is the residual probability that she is a heterozygous carrier?