5. Death cap mushrooms are deadly to mammals because they bind to RNA polymerase and prevent RNA polymerase from working. a. What would be the immediate consequences of eating a death cap mushroom? Eating them may lead to liver and kidney damage as well as death b. Here's a twisted experiment. Feed a mouse a death cap mushroom. Two hours later, take out its liver and do RNAseq on it. What would you expect the data to show? (Hint: remind yourself what RNAseq is, look it up if you need to.)
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The death cap mushroom (Amanita phalloides) is considered one of the world's deadliest mushrooms. The toxicity of the Amanita species is due to the presence of two groups of toxins known as amatoxins and phallotoxins, both made of multiple cyclic peptide chains (circular sequences of bonds). Do some research about the death cap and answer: What makes the Amanita phalloides toxins so harmful that even one cap can kill an adult? Hint: Your short answer should be related to the processes involved in protein synthesis. (Keep your answer short, around 90 words).
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Approximately species of mushrooms are considered lethal 112 100 58
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Toxic Mushrooms? Cadmium, a heavy metal, is toxic to animals. Mushrooms, however, are able to absorb and accumulate cadmium at high concentrations. The Czech and Slovak governments have set a safety limit for cadmium in dry vegetables at 0.5 part per million (ppm). M. Melgar et al. measured the cadmium levels in a random sample of the edible mushroom Boletus pinicola and published the results in the paper "Influence of Some Factors in Toxicity and Accumulation of Cd from Edible Wild Macrofungi in NW Spain" (Journal of Environmental Science and Health, Vol. B33(4), pp. 439-455). Here are the data. $$\begin{array}{cccccc}\hline 0.24 & 0.59 & 0.62 & 0.16 & 0.77 & 1.33 \\0.92 & 0.19 & 0.33 & 0.25 & 0.59 & 0.32 \\\hline\end{array}$$ At the $5 \%$ significance level, do the data provide sufficient evidence to conclude that the mean cadmium level in Boletus pinicola mushrooms is greater than the government's recommended limit of 0.5 ppm? Assume that the population standard deviation of cadmium levels in Boletus pinicola mushrooms is 0.37 ppm. (Note: The sum of the data is 6.31 ppm.)
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