00:01
Hello students here the question is about the renal plasma clearance.
00:04
So renal plasma clearance is defined as the amount of plasma that which is cleared of a substance in a given unit of time and is also known as renal clearance that is based on fick's principle.
00:19
So we have to identify the relation between filtration, secretion and reabsorption along with the renal plasma clearance.
00:26
So the relation is that gfr glomerular filtration rate minus reabsorption rate plus secretion rate equal to clearance.
00:56
So a graph of amount filtered versus amount excreted gives information about reabsorption and secretion but it does not give information on specific regions of nephron on an individual nephron relation.
01:08
So we have to also measure the glomerular filtration rate by inulin.
01:14
So a substance that is completely filtered but neither reabsorbed or secreted is generally used to measure gfr.
01:20
That means inulin is a substance which is completely filtered and is neither absorbed or secreted.
01:28
So inulin is ideal substance to use to measure the gfr.
01:33
So glomerular filtration rate gfr equals to uv by p where u is a concentration, v is a volume of urine flow, p is concentration of substance in plasma concentration of substance in plasma and it is a concentration of substance in urine.
02:15
So the gfr of clearance in this case is 1 to 5 into 1 by 1 equal to 1 to 5 ml per minute because gfr equal to clearance as there is no reabsorption or excretion...