00:01
The question tells about the protein pathway and modifications.
00:07
The basic protein pathway we need to trace from the nucleus to the outer membrane of the cell.
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Nuclease.
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Nuclease is the central organism that controls whole functions of the protein pathway.
00:27
Proteins are transported from the nucleus to cytoplasm.
00:39
Cytoplasm is the site of protein synthesis or the translation process.
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Proteins next transferred cytoplasm to endoplasmic reticulum.
00:54
Endoplasmic reticulum, where varies as a cyclic structures present on the surface of endoplasmic reticulum and is association with ribosomes.
01:15
It is called rough endoplasmic reticulum or rough air.
01:19
Proteins next then transferred into galji bodies.
01:32
Galji bodies are the vascular organes that the.
01:35
Protein packaging takes place here then transfer to secretary vesicles secretary vesicles which transport that protein to specific cell surface or to the cell membrane next we will discuss about protein modification a protein contains one or more polypeptides this protein may not to carry out its function just this protein proteins need to be modifications before it can be function there are two different two different types of protein modifications one is co -translational method co -translational modifications post -translational modifications are the process of changing one or more amino acids in a protein while they are still attached to the ribosomes example acetylation acetylation, during acetylation, methenin is removed from the polypeptide chain.
04:07
Next one, post -translational modifications.
04:27
Most post -translational modifications happen in the endoplasmic reticulum, endoplasmic reticulum and galgi bodies.
04:51
There are several types of post -translational modifications are present in here.
04:57
First one glycolycalization glycocellation glacocellation adding of a carbohydrate group into a protein this is called glycocellation which helps to identify certain cells next lipidation adding of the lipid groove to a protein that generally helps to anchor a protein to the cell membrane next one phosphorylation.
06:06
Very common protein modifications here...