00:01
Hello everyone, in this question we have been asked to describe the synapse and the various neurotransmitters and their mechanism of action.
00:08
So basically there is a presynaptic neuron and a postsynaptic neuron.
00:17
So whenever there is a action potential generated it opens up the calcium channel and due to which calcium enters inside the presynaptic neuron and it lets the synaptic vesicles to fuse to the presynaptic membrane.
00:35
So from this the neurotransmitters that are present inside it after exclusion enters into this phase which is known as synapse.
00:48
So on the postsynaptic neuron we will see there is presence of the neurotransmitter receptors which after receiving these neurotransmitters it opens up the channel.
01:01
Like if there is excitatory acetylcholine then the sodium will enter inside the cell and the potassium will move outside due to which the cell will become depolarized and calcium will move out from the sarcoplasmic reticulum and due to which the muscle contraction will take place.
01:21
So here we have been given acetylcholine.
01:27
So this here can work as excitatory neurotransmitter in case of nicotinic pathway and also the inhibitory neurotransmitters in case of mesoclinic receptors.
01:47
Then we have epinephrine.
01:49
So this epinephrine is basically a excitatory neurotransmitter so due to which the channels will be open.
01:59
Then we have the norepinephrine.
02:03
So this norepinephrine can work as excitatory as well as inhibitory neurotransmitter depending on the excitatory postsynaptic potential or inhibitory postsynaptic potential.
02:20
And then we have dopamine or catecholamines.
02:24
So this dopamine basically are excitatory neurotransmitter.
02:31
Then we have gaba which is gamma amino butyric acid.
02:37
This works as a inhibitory neurotransmitter.
02:41
Then we have glycine which is also an inhibitory neurotransmitter...