00:01
Most of the time when we have a diehybrid cross where we have two totally heterozygous individuals that we cross, like here it's dominant a, recessive a, dominant b, recessive b.
00:10
For both of these individuals, you cross them, you end up with this punnet square.
00:17
Now, when we look at classic mendelian genetics, where you have dominant and recessive genes, you would end up with this phenotypic ratio.
00:28
So you have nine who have both dominant traits, three who have just the a dominant trait, three who have just the b dominant trait, and one out of every 16 who have no dominant traits.
00:43
That is for classic mendelian dominance and recessiveness.
00:48
However, there are a lot of forms of epistasis that can skew this 9 to 3 to 1 ratio.
00:56
I'm going to talk about some of the most common.
00:58
So one of the most common is recessive epistasis.
01:07
For recessive epistasis, we are going to have a nine to three to four ratio.
01:14
And it's just what you would expect.
01:16
We have the nine, which is both dominant traits.
01:20
We have three, which is having the first dominant trait.
01:23
We're having one of the dominant traits.
01:26
But then we find that if there are any chances of having both recessive genes for the first trait.
01:39
If you have any at all, regardless of whether you have dominant or recessive alleles for the secondary trait, you will have one phenotype.
01:49
Right.
01:49
So whether you have two recessive a's and dominant b's or two recessive a's and no dominant b's, you're going to have the same phenotype.
01:59
So in this situation, this double recessive a is your epistasis.
02:06
That's the specific combination of alleles that will override the phenotype and will determine what the offspring will look like.
02:18
Now, there's a similar situation of dominant epistasis.
02:29
In dominant epistasis, we have a ratio of 12 to 3 to 1.
02:36
So 12 is if we have any dominant a.
02:43
So if you have one or two dominant a's, it does not matter what the bs are.
02:49
You will have this certain phenotype because in this case, dominant a is the override...