00:01
So everyone, in this question we will be talking about the epigenetic mechanism.
00:07
So basically this epigenetic changes is caused by the mechanism that is other than the change in dna sequence.
00:17
So this here causes the reversible change that affect the expression pattern of a gene.
00:25
And this is fast from cell to cell by myosis.
00:31
So there are many epigenetic changes like dna methylation.
00:39
So the dna methylation is done on a particular lysine residue of the histone, then it can lead to the transcription inactivation.
00:54
There is also dna ascitalation which basically removes the positive charge from the histone and due to which the dna is no more wrapped around the histone and so it gets unbind and so now transcription factor can get access to the dna due to which the transcription is on.
01:18
There can be done different histone modification that are done on the histone 3.
01:28
And there is also small interference rna and mirna which is utilized for the post -translation modification.
01:42
So this dna methylation can also be seen in the case of x -in -a.
01:48
Activation which leads to the dosage compensation...