DNA nonhomologous end-joining (NHEJ) is the major pathway for repairing DNA double-strand breaks in mammalian cells. Place the following steps in order.
Added by Raymond H.
Step 1
DNA nonhomologous end-joining (NHEJ) is a critical repair mechanism for DNA double-strand breaks (DSBs) in mammalian cells. Here is the step-by-step process of how NHEJ repairs these breaks: --- ** Show more…
Show all steps
Your feedback will help us improve your experience
Suman K and 71 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Select the option that best completes the following statement: Nonhomologous end joining is a process by which a double-stranded DNA end is joined 1. to a similar stretch of sequence on the complementary chromosome. 2. after repairing any mismatches. 3. to the nearest available double-stranded DNA end. 4. after filling in any lost nucleotides, helping to maintain the integrity of the DNA sequence.
Suman K.
In eukaryotic cells, homologous recombination (HR) and non-homologous end joining (NHEJ) are used to repair double-strand breaks. The pathway choice is crucial: HR may be activated even if homologous DNA is not available. In this case, the HR pathway has to be inactivated, and NHEJ needs to be activated. Explain this pathway switch mechanism in detail:
Adi S.
Shaiju T.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD