00:01
Hi, in the question it is given that the drug colchisine is involved in prevention of polymerization of the microtubules and the drug taxol provides stability to the microtubules.
00:21
So in this answer we are going to see which phase of the cell cycle is inhibited by the two drugs and how they do it.
00:38
So colchicine is classified as an anti -inflammatory drug which reduces the swelling which is caused due to inflammation.
00:53
So it is used to treat diseases such as gout, pericarditis, etc.
01:00
Colchicine binds to the tubulin protein which is a component of the microtubule and prevents the polymerization of the microtubules.
01:12
So this inhibits the formation of spindles which takes place during the metaphase of mytotic cycle.
01:21
So it inhibits the metaphase of the mitotic cycle.
01:25
So this inhibition leads to the reduction in the chemotaxis of the inflammatory cell thereby reducing inflammation.
01:35
It also reduces the inflammation inflammation thereby treating inflammation.
01:48
So taxol is a drug which is used to treat tumors of lungs, breast, ovaries etc.
02:02
Taxol makes the microtubules stable by increasing the process of polytubules polymerization of microtubules...