Question

During DNA synthesis on the lagging strand, how come DNA polymerase III activity results in a gap that requires sealing by DNA ligase? Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 3'-hydroxyl group. Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 3'-hydroxyl group. Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but it cannot attach the nucleotide to the 3'-hydroxyl of the next nucleotide. Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but it cannot attach the nucleotide to the 5'-phosphate of the next nucleotide. Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 5'-phosphate group.

          During DNA synthesis on the lagging strand, how come DNA polymerase III activity results in a gap that requires sealing by DNA ligase?
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 3'-hydroxyl group.
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 3'-hydroxyl group.
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but it cannot attach the nucleotide to the 3'-hydroxyl of the next nucleotide.
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but it cannot attach the nucleotide to the 5'-phosphate of the next nucleotide.
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 5'-phosphate group.

During DNA synthesis on the lagging strand, how come DNA polymerase III activity results in a gap that requires sealing by DNA ligase?
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 3'-hydroxyl group.
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 3'-hydroxyl group.
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but it cannot attach the nucleotide to the 3'-hydroxyl of the next nucleotide.
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but it cannot attach the nucleotide to the 5'-phosphate of the next nucleotide.
Because DNA polymerase III can insert the final nucleotide needed to replace the RNA primer, but this nucleotide does not contain a 5'-phosphate group.

Added by Amber C.

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