Endoglucanases and cellobiohydrolases have the same catalytic center but have a variant configuration of the binding site. Identify which of the following is true: Because the catalytic site is identical but the binding site is different, both enzymes can interact with the substrate in different ways, thus producing different catalytic products. Because both enzymes have different binding sites, they catalyze different glycosidic bonds. While cellobiohydrolase cuts the substrate in the middle of the polymer because it has an open-ended tunnel, endoglucanase nibbles at the ends of the polymer because it has a tunnel-like binding site. Both enzymes are beta glucanases; therefore, their functions are identical.