Even though glycolysis only produces 2 ATP, gluconeogenesis has a cost of 6 ATP. Despite this, why does gluconeogenesis still occur? The energy cost is offset by the production of NADH. The glucose will eventually be used in the CAC to generate lots of ATP. The energy cost is offset by the glucose that comes from the diet. Gluconeogensis in the liver makes glucose for tissues that need to use glycolysis for energy.
Added by Jamie D.
Step 1
** Show more…
Show all steps
Your feedback will help us improve your experience
Madhur L and 66 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Glycolysis produces ATP and Gluconeogenesis consumes ATP. If both are operational at the same time: There is no net energy change. ATP produced in one pathway is consumed in the other. Results in net gain of ATP. Energy consumed is less than the energy produced. Results in net loss of ATP. Energy consumed is greater than the energy produced. Simultaneous operation of the two pathways normally does not occur. But it can occur if one organ carries out glycolysis and a different organ carries out gluconeogenesis. both (2) and (4)
Madhur L.
Gluconeogenesis requires the use of 6 nucleotide triphosphate molecules,whereas the glycolytic pathway only yields a net production of 2 ATP molecules during the breakdown of glucose. Why, then would it ever be favorable for the human body to ever produce glucose through the gluconeogenic pathway?
Shaiju T.
Glycolysis only produces a (net) 2 ATP per glucose molecule. This doesn't seem like a lot of energy per glucose molecule, so why is glycolysis used by almost every living organism? Glycolysis and gluconeogenesis are continuously "feeding" each other via the Cori Cycle. So, a lot of ATP can be produced without the need for other pathways. Because this occurs in the mitochondria, which have a lot of folds (cristae), there are a lot of glycolytic enzymes working simultaneously, which produces a lot of ATP. The pathway relies on oxygen, which is very abundant in our atmosphere and used by many organisms. The pathway is incredibly fast, so ATP is produced very quickly.
Sri K.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD