00:01
Question 1 in turn discusses about how interleukin which is written as il, that is interleukin 2 in turn can help to fight against the cancer.
00:10
So here the term cancer in turn denotes uncontrolled cell growth and interlequin is just a molecule that in turn has immunological functions.
00:19
That is it is a small molecule which can have immunological functions and the size of this particular molecule is identified to be 15 .5 kilo -dalton and here can.
00:30
Killodalton intern is represented as kda.
00:34
And this in turn, it is produced or in turn, it works in coordination with certain types of cells that in turn is found in the immune system.
00:44
And the cells which intern will produce is interleukin two molecule is that cd8 positive t cells.
00:51
Here cd8 intern denotes cluster of differentiation.
00:55
And this is one particular cells besides this, it can also be produced by.
01:00
Natural killer cells which is written as nk cells and besides these it can also be produced by dentritic cells which can be returned as dc cells so these are the cells which are which primarily produce this particular molecule and they in turn have very prominent function with regard to the cancer treatment because they in turn repress the growth of tumor formation that is it can lead to regression of tumor cells so thus this is how interleukinto is found to play an role with regard to treatment of cancer.
01:33
Question 2 in turn discuss us about the role played by human monoclonal antibody that is anti -pd 1 with regard to that of the cancer here pd -intern denotes program death 1.
01:50
So this molecule in turn can be explained using the t -cell activation.
01:54
Here with regard to t -cell activation, the t -cells can be activated by the presence of proton molecule.
02:02
Let's write p -t -cell.
02:03
That proton of the pathogen, which in turn needs to be present along with the molecule that is called as mhc molecule, major histocompactivity complex.
02:14
So along with this, there is another recognition required, that is, the cd28 intern needs to be bound with another set of molecule, that is b7 family member, which can be cd80 or cd806.
02:27
So only this recognition in turn can activate the ct cells and this intern can be invalid.
02:33
By one such molecule that is called as ctla fora...