Explain receptor mediated endocytosis and recycling for LDL and the LDL receptor. Describe all of the steps involved. What drives the steps? Where do they occur? What is recycled and what remains in the cell? Why? (5 points) STEPS 1. The receptor functions to internalize LDL. The LDL receptor binds and internalize cholesterol containing particles. 2. There is insisting that is removal of coated pits. 3. It fuses with earphones then formation of early endosome takes place. 4. Endosome contains hydrolytic enzymes there is degradation of cholesterol. The LDL is delivered to lysosomes where it is degraded and it's cholesterol is released for use in the synthesis of membrane, steroid hormones and bile acids. 5. Then transport vesicles are bidding off. 6. Recycling of endosome. 7. LDL receptors are recycled and return to plasma membrane. It occurs in cytoplasm. LDL receptors are recycled, and LDL remains.
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Step 1: LDL particles containing apoB-100 in the bloodstream are recognized by LDL receptors on the cell surface. Show more…
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