00:01
Okay, in order to ask this question, let's talk about glycoying metabolism and also glucose metabolism, okay? it's described like the goals of hormones, insulin, and glucose and glycos and like your metabolism.
00:11
Remember that if this is your liver, glucose is going to get inside.
00:19
It's glucose.
00:20
Glucose is going to get inside.
00:21
And this glucose is going to undergo the process of glycolysis in order to produce atp.
00:29
Okay, glycolysis, and also aerobic sleep inspiration in general.
00:32
Because it is after glycolysis, acetycho is going to be produced and then crept cycle and then osteotif correlation in mitochondria in order to produce atp.
00:42
But what happens if a lot of glucose molecules are entering inside of the liver, then there is going to be very high atp production, even more than this liver needs.
00:54
When that happens, then all of this process is going to be inhibited because you don't need you don't need more atp, you have enough atp for your liver.
01:04
So this glucose is not going to be able to keep going into the glycolysis pathway.
01:12
So in order to not to excrete or waste these glucose molecules, this excess of glucose molecules, it is going to convert or it's going to go into the glycogenesis pathway where it is going to convert into glycogenesis pathway, where it is going to convert into glycogene.
01:31
Okay, this glycogen is a polymer of glucose molecules and it is going to be stored in this, in this form for situations where our body requires more glucose, okay? so this is what is going to happen in glycogen metabolism.
01:48
When we are in fasting states or in stress situations, this glycogen is going to be broken down into glucose by the process of glycogenolysis.
02:00
Okay, and these glucose molecules are going to be set to the blood in order to get to other tissues and use this glucose to produce atp as well as here, okay? so it's as described the goals of the hormones insulin.
02:19
So insulin, insulin is going to, is a hormone that is secreted by the beta cells of the pancreas.
02:27
Okay, and this insulin is going to help glucose molecules or glucose uptake by tissues.
02:37
Because there are some tissues that don't express a transporter for glucose on the cell membrane, like in the liver, for example.
02:43
The liver, there are glute -2 transporters.
02:47
Okay, these are glucose transporters independent of insulin, because they are always expressed there.
02:54
But other tissues, like for example adipocytes, these adipocytes don't have glute -2 transporters, okay? so they have a glut for transporters, but they are here, vesicles inside of this adipocyte.
03:15
In order for them to do exercise and express these receptors here on the cell surface, insulin is required.
03:24
Insulin is going to bind to each receptor here and because of a reduction pathway it is going to lead to correlation of these vesicles and they are going to express this blood for transporters on the surface...