00:01
In this question we are asked about apoptosis which is basically programmed cell death.
00:08
So apoptosis is programmed cell death wherein abnormal cells are eliminated from our body.
00:18
So it is a very regulated and controlled process and it requires many different molecules.
00:26
So the different molecules which are required for the process of apoptosis, firstly we require caspases.
00:37
Now caspases are basically protease enzymes and they are mostly present in an inactive form in our body and they are only active when the cell has to undergo apoptosis.
00:55
So they are only active during apoptosis and they will basically cleave the various substrates so they will help in the cleaving of substrates in the cell so that the cell can undergo programmed cell death.
01:20
Then the second type of molecules required are the bcl2 family proteins.
01:26
Now these are basically the pro -apoptotic and anti -apoptotic proteins.
01:38
So pro -apoptotic and anti -apoptotic.
01:42
Now these proteins are normally present in a balance.
01:50
So these proteins are balanced but once the balance has been disturbed they will lead to apoptosis of the cell.
02:03
Now the third category of proteins which is required which is the cytochrome c complex.
02:14
So cytochrome c it is basically present in the mitochondrial intermembrane space.
02:24
It is present in the intermembrane space and during apoptosis it comes into the cytoplasm and it will basically activate the caspase 9 molecule...