Family Down syndrome is the result of _________ Question 3 Answer A. Translocation B. Investment C. Deficiency D. Genetic duplication
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A child is born with a number of unusual phenotypic features and genetic testing is performed. The child is determined to have partial trisomy 21 , with three copies of some segments of DNA from chromosome 21 , and partial monosomy $4,$ with only one copy of some segments of DNA from chromosome 4. Which of the following mutations could have occurred in one of the parental gametes during development to explain both findings? (A) Deletion (B) Insertion (C) Translocation (D) Inversion
Familial Down syndrome occurs as a result of which chromosomal aberration? a) Inversion b) Robertsonian translocation c) Smithsonian translocation
Sri K.
Select the answer that correctly identifies the various chromosomal aberrations and their respective genetic consequence. a. nondisjunction - aneuploid gametes; duplication $-$ physical and mental abnormalities; deletion - lethal to a diploid organism; inversion-chromosomal breaks in gene; translocations- effects depend on how positions of genes are altered b. nondisjunction - physical and mental abnormalities; inversion - genetic imbalance; duplication - aneuploid gametes; translocations-chromosomal breaks in the gene; deletion -effects depend on how positions of genes are altered C. deletion -aneuploid gametes; translocations-physical and mental abnormalities; duplication -effects depend on positions of genes; nondisjunction - causes genetic imbalance lethal to a diploid organism; aneuploidy-leads to various syndromes d. nondisjunction - chromosomal breaks in gene; duplication - physical and mental abnormalities; deletion - genetic imbalance lethal to a diploid organism; inversion - aneuploid gametes; translocations-effects depend on positions of genes
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