Fatty acids usually have an even number of carbons in their structures. Catabolism of fatty acids produces two-carbon fragments that are converted to acetyl CoA molecules. What is the most likely way in which these acetyl CoA molecules would be metabolized in aerobic cellular respiration? Select one: Oa. They would directly enter the energy-yielding phase of glycolysis. Ob. They would be converted to pyruvate and then undergo pyruvate oxidation upon transport into mitochondria. Oc. They would directly enter the electron transport chain. Od. They would directly enter the citric acid cycle.
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It is not directly involved in glycolysis or the electron transport chain. It also cannot be converted back to pyruvate. Show more…
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Most fatty acids have an even number of carbons and, therefore, are completely metabolized to acetyl-CoA. A fatty acid with an odd number of carb is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. The following two reactions convert propionyl-CoA into succinyl-CoA, a citric acid cycle intermediate, so it can be further metabolized. Each of the reactions requires a coenzyme. Identify the coenzyme for each step. From what vitamins are the coenzymes derived? (Hint: see Chapter 23.)
Fatty acids are broken down into acetyl CoA, which enters the citric acid cycle. If a fatty acid is broken down into 8 acetyl CoA, how much ATP is formed when processing the acetyl CoA in the citric acid cycle? Include ATP formed through oxidative phosphorylation from NADH and FADH2, and include ATP equivalents like GTP. Show all your work.
Adi S.
A fatty acid with an even number of carbons is metabolized to acetyl-CoA, which can then enter the citric acid cycle to be further metabolized (Section 25.10). A fatty acid with an odd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. Propionyl-CoA cannot enter the citric acid cycle. Two coenzyme-requiring enzymes are needed to convert it into succinyl-CoA, a compound that can enter the citric acid cycle. Write the two enzyme-catalyzed reactions and include the names of the required coenzymes.
Raghvendra S.
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