For this and the following FOUR questions answer O if the structure or condition is associated with an open, less condensed form of chromatin OR a C if associated with a closed, more condensed form of chromatin. HISTONE ACETYLATION
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Histone acetylation is a post-translational modification where an acetyl group is added to the lysine residues of histone proteins. This modification is associated with the relaxation of chromatin structure, making the DNA more accessible for transcription. Show more…
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Acetylation of histone tails... A. adds a positive charge to histones and is associated with a less condensed form of chromatin, heterochromatin. B. adds a positive charge to histones and is associated with a less condensed form of chromatin, euchromatin. C. adds a positive charge to histones and is associated with a more condensed form of chromatin, heterochromatin. D. adds a neutral (to slightly negative) charge to histones and is associated with a less condensed form of chromatin, heterochromatin. E. adds a neutral (to slightly negative) charge to histones and is associated with a more condensed form of chromatin, heterochromatin. F. adds a neutral (to slightly negative) charge to histones and is associated with a more condensed form of chromatin, euchromatin. G. adds a positive charge to histones and is associated with a more condensed form of chromatin, euchromatin. H. adds a neutral (to slightly negative) charge to histones and is associated with a less condensed form of chromatin, euchromatin.
Adi S.
There is a growing body of evidence that acetylation of histone N-termini in specific chromosomal regions contributes to gene control by regulating the binding of histones to DNA and the regulation of the folding state of chromatin. The extent of histone acetylation is correlated with the relative resistance of chromatin DNA to digestion by nucleases. Explain which combination of histone acetylation state and DNase 1 resistance is characteristic of actively transcribed regions of chromatin? a) Little or no histone acetylation, highly resistant to DNase 1 b) Little or no histone acetylation, highly sensitive to DNase 1 c) High level of histone acetylation, highly resistant to DNase 1 d) High level of histone acetylation, highly sensitive to DNase 1
Suman K.
Dr. Anas S.
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