Question

a. Contact-Dependent Signaling 1. Form of signaling where the secreted signal causes the original cell to keep secreting the signal. b. Paracrine Signaling 2. This form of signaling would be required in order to recruit immune cells (from the spleen) to a skin lesion on your foot. c. Autocrine Signaling 3. The transmembrane receptor on one cell directly binds to a transmembrane receptor on another cell. d. Endocrine Signaling 4. Small signaling molecules are secreted into the extracellular space where they bind to membrane receptors on nearby cells. 5. Signal molecule (typically a hormone) binds to a target receptor after being transported through the bloodstream. 6. Immortalized cell lines do not respond appropriately to this form of signaling, which is why they are able to overgrow (if not passaged). 7. Form of cellular communication that acts like a positive feedback loop, reinforcing the effects of the original signal molecule.

          a. Contact-Dependent Signaling
1. Form of signaling where the secreted signal causes the original cell to keep secreting the signal.
b. Paracrine Signaling
2. This form of signaling would be required in order to recruit immune cells (from the spleen) to a skin lesion on your foot.
c. Autocrine Signaling
3. The transmembrane receptor on one cell directly binds to a transmembrane receptor on another cell.
d. Endocrine Signaling
4. Small signaling molecules are secreted into the extracellular space where they bind to membrane receptors on nearby cells.
5. Signal molecule (typically a hormone) binds to a target receptor after being transported through the bloodstream.
6. Immortalized cell lines do not respond appropriately to this form of signaling, which is why they are able to overgrow (if not passaged).
7. Form of cellular communication that acts like a positive feedback loop, reinforcing the effects of the original signal molecule.

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a. Contact-Dependent Signaling
1. Form of signaling where the secreted signal causes the original cell to keep secreting the signal.
b. Paracrine Signaling
2. This form of signaling would be required in order to recruit immune cells (from the spleen) to a skin lesion on your foot.
c. Autocrine Signaling
3. The transmembrane receptor on one cell directly binds to a transmembrane receptor on another cell.
d. Endocrine Signaling
4. Small signaling molecules are secreted into the extracellular space where they bind to membrane receptors on nearby cells.
5. Signal molecule (typically a hormone) binds to a target receptor after being transported through the bloodstream.
6. Immortalized cell lines do not respond appropriately to this form of signaling, which is why they are able to overgrow (if not passaged).
7. Form of cellular communication that acts like a positive feedback loop, reinforcing the effects of the original signal molecule.

Added by William E.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

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Solved by Expert Adi S

06/29/2022

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Step 1: The form of signaling where the secreted signal causes the original cell to keep secreting is known as Autocrine Signaling. Show more…

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Form of signaling where the secreted signal causes the original cell to keep secreting the signal: Contact-Dependent Signaling This form of signaling would be required in order to recruit immune cells (from the spleen) to a skin lesion on your foot: Paracrine Signaling The transmembrane receptor on one cell directly binds to the transmembrane receptor on another cell: Autocrine Signaling Small signaling molecules are secreted into the extracellular space where they bind to membrane receptors on nearby cells. Endocrine Signaling The signal molecule (typically hormone) binds to a large receptor after being transported through the bloodstream. Immortalized cell lines do not respond appropriately to this form of signaling, which is why they are able to overgrow when not passaged. Form of cellular communication that acts like a positive feedback loop, reinforcing the effects of the original signal molecule.

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0:00 Cell signaling.

00:01 Cell signaling, it is a form of communication that can be seen between cells and these cells which are located close by can communicate within the small space that is found between them and the cells which are located far away can also communicate using the body fluids such as the blood via secretion and uptake of the liganza.

00:26 So these are the two different forms of signaling and based on this, the first one it is called as the contact dependence signaling return as cds.

00:36 Here contact dependence signaling in turn denotes that the two cells will be placed side by side and then the ligand which is present in one cell will in turn act on the receptor that is present in another cell.

00:50 Here it will be direct interaction between two closely associated cells and next to contact.

00:56 Dependent signaling.

00:58 It is the first other one.

00:59 It is called as the autocrine signaling, which is written as aas.

01:04 Autocrine signaling is that one particular, let's consider one particular cell.

01:09 This cell in turn secretes certain molecules and these molecules in turn will act on the same cell which has produced it.

01:16 So this is called as autocrine signaling.

01:20 And next to it is the paracrine signaling written as pes.

01:24 Paracline signaling is the one which, let's say one particular cell has secreted certain molecules and these molecules will in turn act on other cell which has located some distance away.

01:36 So it will be a little distance away.

01:39 So this is called as a paracrine signaling and this in turn will be taken up by the particular cell which is located some distance away.

01:46 Next to paracrine signaling it is the endocrine signaling.

01:50 It is the endocrine signaling is one.

01:52 One particular cell it will secret it and that molecule in turn will travel via the bloodstream and reach another particular cell.

02:00 So this in turn is denoted as endocrine signaling.

02:04 So with regard to this, the options can be matched as the first one...

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