Question

Four mutants of a particular fungus are called a1, a2, a3 and a4. These four mutants require the amino acid, arginine, to be added to growth media in order for them to survive. Some of these mutants are able to grow however if other compounds which are chemically related to arginine are added to growth medium. Consider the growth patterns of these four mutants in the table below. Note: 0 = no growth; + = growth Mutant | Control | Compounds added to growth medium --- | --- | --- | --- | --- | --- | | Glutamic Semialdehyde | Arginine | Citrulline | Ornithine a3 | 0 | + | + | + | + a4 | 0 | 0 | + | + | + a2 | 0 | 0 | + | + | 0 a1 | 0 | 0 | + | 0 | 0 The scheme below shows a bare outline the normal bio-synthetic pathway for the synthesis of Arginine. Fill in each of the missing mutants (A, B, C, and D) and fill in each of the missing metabolites (E, F, G, and H) by matching these terms with the correct selection. Hint: Consider the Beadle and Tatum experiments. A -> E -> B -> F -> C -> G -> D -> H

          Four mutants of a particular fungus are called a1, a2, a3 and a4. These four mutants require the amino acid, arginine, to be added to growth media in order for them to survive. Some of these mutants are able to grow however if other compounds which are chemically related to arginine are added to growth medium. Consider the growth patterns of these four mutants in the table below.

Note: 0 = no growth; + = growth

Mutant | Control | Compounds added to growth medium
--- | --- | --- | --- | --- | ---
 | | Glutamic Semialdehyde | Arginine | Citrulline | Ornithine
a3 | 0 | + | + | + | +
a4 | 0 | 0 | + | + | +
a2 | 0 | 0 | + | + | 0
a1 | 0 | 0 | + | 0 | 0

The scheme below shows a bare outline the normal bio-synthetic pathway for the synthesis of Arginine. Fill in each of the missing mutants (A, B, C, and D) and fill in each of the missing metabolites (E, F, G, and H) by matching these terms with the correct selection.

Hint: Consider the Beadle and Tatum experiments.

A -> E -> B -> F -> C -> G -> D -> H

Four mutants of a particular fungus are called a1, a2, a3 and a4. These four mutants require the amino acid, arginine, to be added to growth media in order for them to survive. Some of these mutants are able to grow however if other compounds which are chemically related to arginine are added to growth medium. Consider the growth patterns of these four mutants in the table below.

Note: 0 = no growth; + = growth

Mutant | Control | Compounds added to growth medium
— | — | — | — | — | —
| | Glutamic Semialdehyde | Arginine | Citrulline | Ornithine
a3 | 0 | + | + | + | +
a4 | 0 | 0 | + | + | +
a2 | 0 | 0 | + | + | 0
a1 | 0 | 0 | + | 0 | 0

The scheme below shows a bare outline the normal bio-synthetic pathway for the synthesis of Arginine. Fill in each of the missing mutants (A, B, C, and D) and fill in each of the missing metabolites (E, F, G, and H) by matching these terms with the correct selection.

Hint: Consider the Beadle and Tatum experiments.

A -> E -> B -> F -> C -> G -> D -> H

Added by Michael B.

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