Frequency of Recombination and Map Distance • Two linked genes can never be separated by more than 50 mu - Maximum rate if recombination between 2 genes on same chromosome does not exceed 50% • Why? - If 2 genes on same chromosome experience recombination between them 50% of the time, are they linked or unlinked?
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Step 1: When two genes are located close together on the same chromosome, they are considered linked genes. Show more…
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Genes that are far apart on the same chromosome can have a recombination frequency near 50%, but never over that. Why is this? Why can’t we see more than 50% recombinant gametes?
Sri K.
If the recombination frequency between two genes is close to 50%, what could be true about the location of the two genes? A) They are on nonhomologous chromosomes. B) They are far apart on the same chromosome. C) They are very close together on the same chromosome. D) None of the choices could be true E) There has been a translocation event F) they are on non homologous chromosomes
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Why does crossing over occur more often between two distantly linked genes than between two closely linked genes on the same chromosome? Crossing over frequency depends on long-range ordered hydrophobic forces. Two genes that are far apart are more likely to have a crossover between them than two genes that are close together. Crossing over frequency depends on the flexibility of a specific chromosomal region. Two genes that are far apart are more likely to have a crossover between them than two genes that are close together. Crossing over is somewhat randomly distributed over the length of the chromosome. Two loci that are far apart are more likely to have a crossover between them than two loci that are close together.
Suman K.
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