Fatty Acid Catabolism
1.(0.25)The primary storage form of lipid is
and it is normally stored in the
a. phospholipid; liver
b. cholesterol; muscles
c. monoacylglycerol; adipocytes
d. triacylglycerols; adipocytes
e. triacylglycerols; liver
2.(0.25) The sequence for activation of the release of fatty acids from adipose cells is
A. protein kinase activation
B. cAMP production
C. triacylglycerol lipase activation
D. fatty acid binding to serum albumin
E. hormone binding receptor
F. adenylyl cyclase activation
G. diacylglycerol lipase and monoacylglycerol lipase
a. B, G, A, D, E, F, C
b. D, E, B, A, F, G, C
c. E, B, C, G, A, F, D
d. E, B, G, D, A, C, F
e. E, F, B, A, C, G, D
3. (0.25) In words, describe the reaction of a lipase, including the EC class of the enzyme.
(0.25) EC classification of lipases:
(0.5) Draw the chemical structures for a lipase reaction, naming the enzyme and cofactors.
4.(0.25) Bile salts are important in the initial digestion of triacylglycerols in the intestine because they:
a. are coenzymes for pancreatic lipase.
b. convert the inactive lipase into the active form.
c. emulsify the triacylglycerol globules to produce greater surface area which will increase the activity of the lipase.
d. activate the cleavage at the C-2 position.
e. permit greater permeability of the triacylglycerols through the intestinal membrane.