Genetics Pedigree Analysis: A) Draw all possible conclusions concerning the mode of inheritance of the trait expressed in the pedigree below. Explain why it could be Autosomal Dominant/Recessive and X-linked Dominant/Recessive. B) Given the most probable mode of inheritance, what is the probability that II-8 & II-9 are unaffected? C) If the first child is affected, II-8 and II-9 have 3 more children, then indicate the probability that at least one child is affected?
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The trait is expressed as a recessive gene. Show more…
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Pedigree analysis a. What is the most likely mode of inheritance for the phenotype illustrated in the pedigree below? Justify your answer based on the inheritance pattern. b. Who must be a carrier in this pedigree, and what offspring justifies this conclusion? c. Given the inheritance pattern, what is the likelihood that individuals I.1 and I.2 could have 3 male children who are unaffected? d. Would this inheritance pattern affect breeding strategies if the trait is deleterious?
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The accompanying pedigree is for a rare, but relatively mild, hereditary disorder of the skin. 1 II II IV a. How is the disorder inherited? State reasons for your answer. b. Give genotypes for as many individuals in the pedigree as possible. (Invent your own defined allele symbols.) c. Consider the four unaffected children of parents III- 4 and III- $5 .$ In all four-child progenies from parents of these genotypes, what proportion is expected to contain all unaffected children?
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