00:01
Okay, so this question asks about the various biochemical functions of glutamine, as it is given intravenously, for helping recover from surgery injuries and burns.
00:18
And then it asks about each of the variety of biochemical functions that glutamine has and asks us to provide biochemical rationales for each of these biological functions.
00:31
Functions.
00:32
So we're going to start from the top and go down the list for what these functions are.
00:41
So first of all, we have substrate for gluconeogenesis.
00:44
The substrates for gluconeogenesis are glycerol, lactate, and amino acids.
00:51
And for b, we have oxidative fuel to make cellular energy and the rationalize of the carbon in fuel molecules such as glucose and fats, it's oxidized, to carbon dioxide and the energy released is used to regenerate atp from adp and phosphate ion.
01:09
And so for d or c, we have the rationale is that non -toxic transporters of ammonia in the liver.
01:20
And glutamine essentially acts as a non -toxic transporter of ammonia in the liver.
01:25
And ammonia is loaded via glutamine synthetase by the reaction nh3 plus squibrate.
01:32
Which yields glutamine.
01:35
For d, we have acid -based balance in the kidney...