Gustducin is a protein required for sensing tastes such as sweet and bitter. Gustducin is very similar to transducin – in fact, experiments show that gustducin can fully substitute for transducin when expressed in rod cells. Which of the statements below are true? Choose four! In the GDP-bound form, the alpha-subunit of gustducin does not bind the beta- and gamma-subunits. Sweet and bitter tastes are sensed by G-protein coupled receptors (GPCRs). Activated gustducin inhibits its effector PDE6 (phospho-di-esterase 6). Cyclic GMP (cGMP) is a second messenger in the signal transduction pathway for sensing sweat and bitter tastes. Gustducin is a nuclear protein. The sensors of sweet and bitter tastes are guanine nucleotide exchange factors (GEFs). Gustducin can catalyze hydrolysis of GTP into GDP and inorganic phosphate. Activated gustducin activates its effector GC (guanylate cyclase).
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Gustducin is a G-protein involved in the detection of sweet and bitter tastes. It is similar to transducin and can substitute for it in rod cells. Gustducin is part of a signaling pathway that involves G-protein coupled receptors (GPCRs). Step 2: Evaluate the Show more…
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