Question

How does a defect in ADA cause the immune disease ada scid? Cells are no longer able to comtrol the level of dntps, ada deficiency blocks production if tibose-5p, ada defect increases datp, ada deficiency causes buildup of 2-deoxyribose-5p, or ada scid is caused by mutations in the r1 subunit

Name: how does a defect in ada cause the immune disease ada scid cells are no longer able to comtrol the level of dntps ada deficiency blocks production if tibose 5p ada defect increases datp ada 57623
Uploaded: 2023-07-27T11:48:38-08:00
Duration: 4 min 28 s
Channel: Asma Venkitta
Description: how does a defect in ada cause the immune disease ada scid cells are no longer able to comtrol the level of dntps ada deficiency blocks production if tibose 5p ada defect increases datp ada 57623

          How does a defect in ADA cause the immune disease ada scid? Cells are no longer able to comtrol the level of dntps, ada deficiency blocks production if tibose-5p, ada defect increases datp, ada deficiency causes buildup of 2-deoxyribose-5p, or ada scid is caused by mutations in the r1 subunit

Added by Kimberly M.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

Instant Answer

Solved by Expert Asma Venkitta

07/27/2023

Step 1

The high dATP inhibits ribonucleotide reductase, leading to imbalanced and depleted dNTP pools that are required for DNA synthesis and repair. Show more…

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How does a defect in ADA cause the immune disease ada scid? Cells are no longer able to comtrol the level of dntps, ada deficiency blocks production if tibose-5p, ada defect increases datp, ada deficiency causes buildup of 2-deoxyribose-5p, or ada scid is caused by mutations in the r1 subunit