I need help, please.
When hematopoietic stem cells are collected before radiation treatment, then given back to the same patient after radiation treatment, this is called what?
Allogeneic transplant
Autologous transplant
Syngeneic transplant
Monoclonal antibody therapy
Name the disease: Expression of tissue-specific genes in the thymus is defective, resulting in polysyndromic autoimmune disease.
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
Hashimoto's disease
Graves' disease
Type I diabetes
Systemic lupus erythematosus (SLE) is characterized by intermolecular epitope spreading because:
CD4 T cells recognize one epitope on a molecule that confers reactivity to an epitope recognized by CD8 cells
CD4 T cells bind to the same epitope sequence that is repeated within one molecule
CD4 T cells recognize the same epitopes spread across different molecules
CD4 T cells specific for one epitope of a macromolecular complex can provide help to B cells specific for another accessible epitope of the complex
Which statement about systemic anaphylaxis is incorrect?
It results from an antigen in the bloodstream causing widespread mast cell activation
It is a rapid process in sensitized people
It is triggered by an underlying Th2 response
Its effects can be severe, even lethal
Genetic polymorphisms are known to be important in susceptibility to allergy. Which genes are unlikely to influence susceptibility to Type I hypersensitivity?
HLA-A, HLA-B, and HLA-C genes
HLA-DP, HLA-DQ, and HLA-DR genes
IL-4 receptor gene
IgE receptor gene