1B) What is the probability that B3 is a carrier of this...

1B) What is the probability that B3 is a carrier of this disorder? Show your work with a Punnett Square (0.75pts) in addition to stating the probability (0.75pts). 1C) Individuals C2 and C3 are considering having additional children. However, having already had a child with this disorder, they visit a genetic counselor to determine what the probability is that their future child would have the disorder. If C2 and C3 have another child, what is the probability that the child will have the disorder? Show your work with a Punnett Square (0.75pts) in addition to stating the probability (0.75pts). 1D) D5 goes on an exotic vacation and meets the love of her life, Taylor. It is determined that 10% of the population where Taylor lives is a carrier for this disorder. If we assume Taylor has the same risk of being a carrier as everyone else in their population (10%), what is the probability that D5 and Taylor will have a child with the disorder? Show your equation and explain for full credit (2.5 points—1.5pts for equation with explanation or Punnett Squares, 1pt for correct probability).

Transcript

00:01 In order to answer this question, let's talk about inheritance.

00:04 Let's start with the first question.

00:06 It says, what is the probability that b3 is a cover of this disorder? and well, we have a pedigree here, apparently.

00:12 And well, this is our pedigree.

00:14 So in order to determine the chances that b3 is a carrier, we have to first determine the inheritance pattern of this pedigree.

00:24 So this disease, first, it is not dominant.

00:26 Because in dominant diseases, you don't have covers.

00:29 And apparently, you have covers here.

00:31 Because, well, first because that question is telling you about a caviar, and also because this man has the mutant allel, and this mutant allel was given from one of the parents.

00:41 So it means that at least one of the parents has a mutant allel, but they are not expressing the disease.

00:46 So it means that you have cavares in this pedigree, and hence it is not dominant.

00:51 Now, is it ex -link recessive or autosomal recessive? well, it is autosomal recessive because in x -ling recessive, then this woman would have two mutant ex -allel.

01:01 So one ex -allel should come from the mother, and the mother can be a cavern, so it fits up to here.

01:07 But the second recessive allele should come from the father, and the father is healthy.

01:13 So if the father was to have a mutant allele, then he would be, or he would have a disease, because males only need one mutant -ex -allel in order to express a disease.

01:24 So this pedigree is not ex -linked and it is auto -summer recessive.

01:30 So now, here, remember that a person inherits one allele from each parent.

01:38 If it is autosomal recessive, it means that this boy here, for example, is homozyglysis, like this.

01:44 So it means that one recessive allele came from the mother and one recessive allel came from the father.

01:49 So both parents have at least one recessive allele.

01:52 So they can be heterocygoseal excessive, but as you can see here, both don't have that disease.

01:57 So they are not or they are not homozygous excessive, but heterocygote.

02:01 Both of them.

02:06 Okay, these are the genotypes for these individuals here.

02:09 And with it, we can answer the questions.

02:11 It says, for question number one, that says, what is the probability that b3 is a cagrefer of this disorder? we have to make up a square for the parents that are heterozygos and heterocygios.

02:23 You have homocygios dominant.

02:24 You have heterozygios, you have hydrozygos, and you have homozygose.

02:28 Recessive.

02:29 So, here you have a total of four possibilities, but you are not going to use the four here, because you already know that this b3 does not have the disease, right? so it means that you're going to take only one, two, and three as a total.

02:46 So you have a total of three.

02:48 And out of three, one and two are powers.

02:52 Caves are the same as heterocycles.

02:54 Okay, so you have two thirds chances for b3 to be heterocycles.

02:59 And it says show your work and in addition stating the probability...

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