Identify the GTP bound protein which initiates the signal transduction, after the receptor tyrosine kinases gets activated by autophosphorylation
Added by Dwayne B.
Step 1
** Show more…
Show all steps
Your feedback will help us improve your experience
Adi S and 69 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
How does the binding of a signal molecule activate an RTK for downstream signaling? ----> The RTK forms a dimer and cross-phosphorylates itself. ----> The RTK is an ion channel that opens in response to ligand binding. ----> The RTK changes conformation to stimulate a G-protein. ---> The RTK undergoes a cleavage event to release the cytosolic portion. Question-2: Which of the following is NOT an intracellular signaling protein activated by an RTK? a. PI-3-kinase b. Trimeric G-proteins c. Ras d. monomeric GTPase Question-3: The active form of a monomeric GTP-binding protein is the.... a. GTPase-activating protein (GAP). b. GTP-bound form. c. guanine nucleotide exchange factor (GEF). d. GDP-bound form
Adi S.
G-protein-coupled receptors ____, whereas receptor tyrosine kinases ____. A are cytoplasmic proteins; form a dimer to fully activate B are not enzymes; have enzymatic activity C act by phosphorylating a protein; open an ion channel when bound to a signal molecule D form a dimer to fully activate; catalyze the transfer of a phosphate group
Sukhada S.
Sri K.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD