Identify the true statements about RNA interference. Select all the true statements. A. miRNA is cleaved by Dicer enzyme complex B. Duplex RNA (dsRNA) can suppress the expression of a gene. C. miRNAs are short duplexes approximately 21 nucleotides long D. miRNAs suppress gene expression by interfering with transcription E. RNA interference can temporarily suppress the expression of a target genes
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Dicer is an enzyme that processes precursor miRNA molecules into mature miRNA molecules. Show more…
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Which of these statements are correct about the RNA interference pathway? MORE THAN 1 CORRECT! No explanation needed. A- It has probably evolved as a defense mechanism against viral infection, as viral RNAs can be cleaved by Dicer into siRNA molecules, which target the original viral RNA for destruction by the RNAi pathway. B- The pathway can be exploited in the lab to knock down expression of a gene of interest. C- Different types of short RNA molecules can feed into the RNAi pathway: endogenous miRNAs, siRNAs generated from invading viral RNA molecules, and synthetic siRNA and shRNA molecules transfected into cells. D- Dicer cleaves the precursor miRNAs before export from the nucleus. E- One miRNA is specific for only one particular mRNA transcript whose expression it regulates post-transcriptionally.
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